Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured ...

During early development, the embryo builds the body's organs by exchanging chemical signals between different cell types. When developing limbs, a thin band of skin cells at the limb’s surface, ...

This figure illustrates that TBX4 is crucial for mammalian limb development during the embryonic stage. It activates FGF10 within the mesoderm and interacts with β-catenin in the Wnt pathway, driving ...

Scientists have created a spatial atlas of the incredible process of human limb development, including steps that show digits emerging from a bud as cells recede, instead of growing outward. With ...

So they turned their attention to the Iberian ribbed newt, which can regenerate not only body parts that are cut off but parts of its heart as well. There they focused on a molecule known as ...

Although often glossed over, the human liver is a pretty amazing organ. Not just because it’s pretty much the sole thing that prevents our food from killing us, but also because it’s the only organ in ...

In a new study published in Nature Communications, EPFL researchers shed light on the axolotl's unparalleled limb regeneration abilities, challenging long-held beliefs and offering new insights into ...

Fins and limbs and fins into limbs : the historical context, 1840-1940 / Peter J. Bowler -- Skeletal changes in the transition from fins to limbs / Michael I. Coates and Marcello Ruta -- A historical ...