The field of proteomics has undergone rapid advancements over the last decade and protein microarrays have emerged as a promising technological platform for the challenging task of studying complex ...
Figure 3: Genome-wide mapping of DNA copy-number variation for breast cancer cell line BT474. Figure 4: High-resolution analysis of recurrent amplicons in breast cancer. Figure 5: Parallel analysis of ...
This Proven Technology Continues To Find Its Niche in the Modern Molecular Toolkit The advent of microarray technology has a much longer history than many realize. Ask any scientist “What is a ...
Most pharmaceuticals sold today have their origin in a biochemistry laboratory. Drug discovery has traditionally started with a biochemical pathway implicated in a pathophysiological process. An ...
Small molecule microarrays allow screening of biomolecules such as peptides and carbohydrates. By immobilizing these small molecules on a microarray, interactions can be quickly assessed through a ...
Regarding the articles on microarrays, 1-3 Pat Brown and the group at Stanford deserve great recognition for their technological innovations that led to widespread use of microarray analysis in ...
While microarray technology is broadening its applications in genomics and proteomics, the technique remains a vibrant contributor in the area of gene expression. Much of the overall developmental ...
With a protein microarray, researchers can find a specific protein in a biological sample, allowing them to diagnose a disease or unravel a physiological process. But sometimes one protein in one ...
The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...
The biggest news these days in tissue microarrays (TMAs) may be that this former "next big thing" has become a standard tool for molecular profiling of disease. Some 682 papers have been published on ...
*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...