Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Proteins are made of chains of amino acids, and a basic tenet of biology is that the sequence of amino acids determines how a protein folds into a 3D shape which, in turn, dictates the protein’s ...

Researchers from the University of Science and Technology of China (USTC), led by Prof. Liu Qi, in collaboration with Harvard Medical School's Marinka Zitnik lab, have developed a novel deep ...

Researchers at Pacific Northwest National Laboratory used artificial intelligence to analyze protein nanoribbons, pointing to ...

Protein design aims to create customized antibodies for therapies, biosensors for diagnostics, or enzymes for chemical reactions. An international research team has now developed a method for ...

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...

A multicolored 3D model of an enzyme binding double-stranded DNA against a light purple background Computational enzyme design could allow for reactions not seen in nature. Credit: Ian Haydon ...

Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...

Manifold Bio, a platform therapeutics company pioneering direct-to-vivo drug discovery, today announced a joint study with NVIDIA to validate Proteina-Complexa, NVIDIA's generative model for protein ...

The “ChatGPT moment” for biology proceeds to unfold as protein language models, or machine learning tools trained on large databases of protein sequences, work to decode the language of life with the ...