A study has described a mechanism that plays a key role in the evolution of Alzheimer’s disease. According to the paper, the activation of the protein Sirtuin 1 in a murine model with familial ...

For decades, scientists have been searching for the fundamental biological secrets of how eating less extends lifespan. Scientists have now described a molecular pathway that is a key determinant of ...

There's a growing belief in scientific circles that the old theory that aging is the natural result of gradually tiring cells isn't accurate. Instead, many researchers are advocating a new approach, ...

Keeping mitochondria healthy may be the secret to a long life, according to new work on the sirtuins, a family of enzymes that regulate aging and lifespan. The research shows that cells under stress ...

Autophagy is a process by which cells engulf and degrade their own damaged organelles and aggregated proteins. This self-cleaning feature is critical to the health of neurons, and its loss in the ...

Scientists discovered that changing stem cells’ energy source from glucose to galactose creates “super stem cells” with enhanced abilities and developmental potential. This metabolic switch activates ...

Sirtuin 3 (Sirt3)-modified mitochondrial fission participates in the progression of several types of cancers. However, its role in tongue cancer requires investigation. The aim of our study is to ...

A glass of red wine might hold a certain mystique, but its mystery on a molecular level runs far deeper. That’s largely because of resveratrol, a compound in red wine and many plants. In animal tests, ...

MADISON — For decades, scientists have been searching for the fundamental biological secrets of how eating less extends lifespan. It has been well documented in species ranging from spiders to monkeys ...