Changes Clinical Practice: Based on this large trial, lithium alone or a lithium-valproate combination should be used as first-line maintenance treatment for bipolar affective disorder type I instead ...

For people with bipolar I disorder*, for whom long-term therapy is clinically indicated, both combination therapy with lithium plus valproate and lithium monotherapy are more likely to prevent relapse ...

July 25, 2011 — Lithium is more effective in treating episodes of bipolar disorder (BD) than valproate. However, there is little difference between the 2 agents in reducing suicidality in this patient ...

Please provide your email address to receive an email when new articles are posted on . Absolute 10-year CKD risks were similar in both the lithium and valproate groups. Of more than 35,000 routine ...

Long-term mood stabilizer use in bipolar disorder Mixed and psychotic features and comorbid anxiety disorder were also associated with poor treatment response. About one-third of patients receiving ...

Compared with lithium, valproate, olanzapine, quetiapine, and risperidone generally exhibited a lower likelihood of thyroid dysfunction. HealthDay News — Lithium is associated with an increased risk ...

Hayes et al 12 conducted one of the most recent large studies to compare lithium with newer second-generation antipsychotics as maintenance monotherapy for bipolar disorder. The authors concluded that ...

Higher lithium serum levels linked to elevated rates of hypothyroidism, hyperthyroidism, and CKD3+. (HealthDay News) — Lithium is associated with an increased risk for thyroid dysfunction and chronic ...